ICU危重病人常伴应激性高血糖,这种急性一时性的高血糖可产生有害的病理生理效应。胰岛素反向调节激素的分泌增加,细胞因子的大量释放和胰岛素抵抗是产生应激性高血糖的主要原因。近年来研究显示胰岛素强化治疗将血糖控制在4·0~6·1mmol/L范围内能有效地减少高血糖所致的并发症,促进疾病的恢复,改善疾病的预后。现就此方面的研究进展作一简介。 ICU critically ill patients often accompanied by stress hyperglycemia, this acute and temporary high blood sugar can have harmful pathophysiological effects. Increased secretion of insulin reverse regulatory hormones, a large number of cytokine release and insulin resistance is the main reason for stress-induced hyperglycemia. In recent years, studies have shown that intensive insulin therapy will be blood sugar control in the range of 4 ~ 0 ~ 6 · 1mmol / L can effectively reduce the complications caused by hyperglycemia, promote disease recovery and improve the prognosis of the disease. Now on the research progress in this area to make an introduction.