Dnlg2 regulates DGluRs recruitment via dPak function in the actin cytoskeleton

来源 :第二届中国果蝇大会 | 被引量 : 0次 | 上传用户:refreshingmind
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Neuroligin is a highly conserved family of cell adhesion molecules which are implicated in synapse formation and function.Previous studies have already showed Drosophila neuroligin2 (dnlg2) mutants exhibit a decrease in the total glutamate receptor density and size of dPak (p21-activated kinases) clusters.However,the mechanism of regulation of glutamate receptor by dnlg2 is still remains unclear.
其他文献
  Neuroligin (NLG),a postsynaptic adhesion molecule,is thought to perform essential functions in synapse validation and synaptic transmission by binding to ne
  脂肪体是昆虫体内的一个非常重要的内分泌器官,也在其物质代谢和能量代谢中起着重要作用.全变态昆虫例如果蝇在变态期间,其脂肪体会从完整的片状或者带状变为许多游离在
  Angelman syndrome (AS) is a neurodevelopmental disorder characterized by severe mental retardation,motor dysfunction,lack of speech,ataxia and developmental
会议
  The trans-membrane molecules in asymmetric junction play important roles in signal transduction during the differentiation and maturation of neurons.The pre
  自作者等在上世纪九十年中叶利用果蝇模型证明经典Wg/Wnt信号途径调控心脏发育的作用后,国际同行在本世纪相继利用斑马鱼、非洲爪蟾和小鼠模型反复证明了该信号对心脏器官
会议
  原神经基因表达诱导并决定神经前体细胞,后者经过一系列的增殖、分化,最终形成神经系统.原神经基因的发现与命名源于果蝇,并由此引发了对其他动物(非脊椎动物与脊椎动物)
  我们组之前的研究表明,果蝇能够在嗅觉和视觉两种模态间传递记忆。在此基础之上,我们进一步探讨了果蝇的跨模态记忆抽提机制。传统的理论认为在感觉预条件化(sensory preco
目的 探讨新橙皮苷二氢查耳酮(NHDC)体外抗对乳腺癌细胞增殖的影响.方法 1.将不同浓度的NHDC干预正常乳腺上皮细胞MCF-10A、乳腺癌MCF-7(ER+)和MDA-MB-231(ER-)细胞72小时后,
  有限空间内果蝇的群体飞行行为是一个随机过程。迄今为止,在自然空间下诱导果蝇群体形成有效自组织行为的条件并不清楚。用远程光学手段计算机视觉技术可以对数百只果蝇在
  Neuroligins (Nlgs),the neural adhesion molecules,are thought to be required in synaptogenesis and functions via binding to their partners Neurexins (Nrxs).H