A Nanoengineered Peptidic Delivery System with Specificity for Human Brain Capillary Endothelial Cel

来源 :纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会 | 被引量 : 0次 | 上传用户:huninbo
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
The blood-brain-barrier (BBB) is a formidable obstacle for successful translocation of many drug molecules from the systemic circulation into the brain, and therefore a major challenge for development and launches of neurotherapeutics.
其他文献
Micelles self-assembled from amphiphilic copolymers have become one of the most promising carriers of anticancer drugs, manifesting several attractive features such as the core-shell structure to effe
会议
INTRADUCTION Gene transfer vector is one of the key technologies of gene therapy.Gene carriers generally can be divided into two major categories of virus and non-virus, the former is subjected to sec
Triggering the mitochondrial apoptosis pathway to cause cancer-cell suicide is a potential option for cancer therapy [1].However, the therapeutic effects of drugs that act on mitochondria were not rem
会议
D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS or Vitamin E TPGS) is a water-soluble derivative of natural Vitamin E, which has been applied in drug delivery systems since it is an FDA approv
会议
The structure of building blocks or components often has a significant impact on the performance of nanoparticles as drug carriers.It is well known that many micelle, emulsion and liposome formulation
会议
Cytokines-induced Killer therapy (CIK) has been used for clinical therapy as the third therapeutic technique.However, how to enhance CIK immunotherapeutic effect in cancer targeted immunotherapy and p
会议
Cellular delivery is an important concern for the efficiency of medicines and sensors for disease diagnoses and therapy.However, this task is quite challenging.
Polymeric micelles represent a promising drug carrier system that has gained considerable attention due to its simplicity, small sizes, and the ability to solubilize water-insoluble drugs and accumula
会议
Generally, combination chemotherapy refers to two or more therapeutic agents delivered simultaneously, which is established to minimize the amount of drug, reduce frequency of drug administration, and
会议
Green synthesis, especially in biological processes, has gained more attention with increasing application of naosilver in biomedical fields [1].However, the biologically synthesized nanoparticles hav
会议