【摘 要】
：
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease that is characterized by excess triglyceride (TG) accumulation in the abse
【机 构】
：
State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology, 130
【出 处】
：
2015年上海市研究生学术论坛(生物化工)
论文部分内容阅读
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease that is characterized by excess triglyceride (TG) accumulation in the absence of excessive alcohol intake.This disease can progress to inflammatory nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis,and endstage liver injury in humans.The validated treatment in NASH is to reduce progression to advanced fibrosis, cirrhosis, and its sequelae.However, the optimal treatment remains uncertain.The fiver plays an important role in the metabolism of many elements, including metals, which are mandatory for the function of biological systems.However, the linkage and interplay between metal elements and steatosis in liver tissue is not clarified and is the subject of this study.
其他文献
薄荷醇是世界第三大香料,广泛用于医药、食品、烟草、化妆品等产品。现阶段利用生物催化手性拆分技术制备l-薄荷醇的研究中薄荷酯的酰基取代部分主要为脂肪族羧酸,已有很
迟钝爱德华氏菌(Edwardsiella tarda E.tarda),革兰氏阴性菌,肠杆菌科(Enterobacteriaceae),可以感染重要的海洋水产鱼类(大菱鲆、牙鲆等),使其患有出血性败血症、肠道感
光催化分解水制氢技术是一种使用半导体光催化剂，将太阳能转化为化学能，催化分解水生成氢气的技术。该技术将地球上最丰富的可再生能源转化为化学能储存于氢气中，是一种具有
两水相萃取是一种新型的生物分离技术，主要包括聚合物-聚合物，聚合物-盐等体系种类。它具有本身独有的特点：系统的含水量高；操作条件温和，对分离的物质的活性无破坏作用；易于放
首先，在固体平板上观察光照对海洋丝状真菌Halorosellinia sp.菌落生长和形态的影响.接着，在已优化的培养基之上，通过摇床发酵考察不同的光照强度和光脉冲策略对海洋丝状真
Enantioselective hydrolysis of racemic epoxides mediated by epoxide hydrolases (EHs) is one of the most promising approaches to obtain enantiopure epoxides.
TiO2具有无毒、高活性、高稳定性及非常强的抗氧化能力等优点，是目前最具开发前景的绿色环保型催化剂.二氧化钛的宽带隙(3.2eV)导致太阳能利用效率低，限制了其实际应用.为
口蹄疫是一种传播无国界的全球性传染病，可引起巨大的经济损失和严重的公共卫生问题，故常被称为"政治经济病"。其一旦暴发，能迅速演变为生物灾害。大批的动物被扑杀销毁，引发
Backgrounds: In this study, the performance of aerobic batch fermentation with Aspergillus niger producing sodium gluconate under different oxygen supply le
咪康唑是高效、安全、广谱抗真菌药,对致病性真菌几乎都有作用.其机理是抑制真菌细胞膜的固醇合成,影响细胞膜通透性,抑制真菌生长,导致死亡.本品是西安杨森在国内药品市