The effects of intensive atorvastatin on contrast induced nephropathy after percutaneous coronary in

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Background Contrast induced nephropathy (CIN) is a common complication after percutaneous coronary intervention(PCI).Due to the poor ability of kidney reserve and compensation in elderly patients with coronary heart disease, CIN was prone to be occurred under this condition.Therefore, searching for effective strategies to prevent CIN in elderly patients of coronary heart disease is of essential importance.Statins can produce a protective effect to renal function to some extent due to its multiple biological effects, however, it remains great controversies about whether statins can prevent the occurrence of CIN, the appropriate dose and mechanism at present.
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