【摘 要】
：
DNA complex has been widely used as non-viral vectors for the delivery of genes or siRNA.Owing to the strong and long-ranged electrostatic interaction, the structure and property of the DNA complex sh
【机 构】
：
Beijing National Laboratory for Molecular Sciences,Key Laboratory of Polymer Chemistry & Physics of
【出 处】
：
Seventh International Symposium On Engineering Plastics (第七届
论文部分内容阅读
DNA complex has been widely used as non-viral vectors for the delivery of genes or siRNA.Owing to the strong and long-ranged electrostatic interaction, the structure and property of the DNA complex should evolve with time in a long-term To test this hypothesis, we choose 2000 bp double-stranded DNA and 21 bp oligonucleotide as the model molecules, and comparatively studied their complexation with narrowly-distributed poly-L-lysine (PLL150) by time-resolved laser light scattering.In the time range of about one week, the complexation of both DNA samples underwent three stages: formation of preliminary complex, further aggregation, followed by precipitation.The aggregation and precipitation rate of the complex formed by oligonucleotide was much faster than that of the complex formed by 2000 bp dsDNA.
其他文献
化工产业基本情况河南能源化工集团是2013年9月12日经河南省委、省政府批准,由河南煤化集团与义马集团战略重组成立的国有独资公司,是一家集煤炭、化工、有色金属、装备制造、物流贸易、建筑矿建、现代服务业等产业相关多元发展的特大型能源企业集团.化工产业是河南能源化工集团重点打造的核心支柱产业,目前拥有35家化工企业、94套装置、18种主要化工产品,涉及煤化工、盐化工、精细化工和工程塑料等多个领域,主要
"Moving from product focused to process focused development" A Brief History of Keysight Technologies 1939-1998: The Hewlett-Packard years A company founded on electronic measurement innovation 1999-2
公司简介企业名称:上海东硕环保科技股份有限公司股票代码:836487"新三板"挂牌主业范围:工业废水"零排放"注册资本:1.06亿元年产值:9.5亿元人民币Ownership Structure 上海东硕环保科技有限公司(中外合资)公司荣誉国家高新技术企业中国环保产业骨干企业 中国环保产业协会常务理事单位煤焦化废水处理产业联盟牵头单位国家科委创新基金及小巨人3项 国家资助 500万元上海市科委学科
氮氧化物(NOx)是大气污染的主要有害物质之一,氮氧化物有N2O、NO、NO2、N2O3、N2O4和N2O5,总称为NOx,其中污染大气的主要氮氧化物是NO和NO2.大气中的氮氧化物是形成酸雨酸雾的主要污染物,同时破坏臭氧层,形成光化学烟雾,对人体具有致毒作用.因此,在燃烧过程中,必须对氮氧化物的排放进行严格控制.2015年1月1日开始执行的国家标准《炼焦化学工业污染物排放标准》对大气污染物NOx
For more than two decades, toughening of epoxy resins is one of the major topics in the field of thermosetting composites.Besides several approaches, the use of nanoparticles is very promising, since
Shape memory polymers (SMPs) are materials that can change their bulk shape in response to a vast array of external stimuli such as heat, light and electric field,1-4 The initial and final shapes of S
Microbial polyhydroxyalkanoates (PHA) have been developed as bioplastics for the past many years.Commercial PHA arc normally poly-3-hydroxybutyrate (PHB), copolycsters of 3-hydroxybutyrate and 3-hydro
Palm oil is an important commodity and renewable resource with a wide range of applications.Palm oil is also the words most efficiently produced vegetable oil.Stable market price and good agricultural
The development and production of biodegradable starch-based materials have been spurred by oil shortages and the growing interest in casing the environmental burden of petrochcmically derived polymer
A series of new functional amino acids were prepared in high yield via thiol-ene Michael addition between L-cysteine and monomethoxy oligo(ethylene glycol) (OEG) functionalized methacrylates (OEGxMA)