Objective: Cardiovascular events still occupy the first cause of mortality in type 2 diabetes mellitus (T2DM), which comes down to the metabolic syndrome.
Exogenous melatonin (Mel) is widely used in clinic for multiple therapeutic purposes.In metabolism pathways of Mel,6-hydroxymelatonin-sulfate (S-O-Mel) and
Benzbromarone (BBR) is a benzofuran derivative that has been a quite useful drug for the treatment of gout.However, it was withdrawn from European markets i
Aim: The flavonols are believed to be the pharmacologically active ingredients of ginkgo biloba extract and show a wide variety of biological activities.
Chemical of herbal products may cause unexpected toxicity effect by the potential for alteration of the activity of human cytochrome P450 enzymes (CYP450s)