【摘 要】
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The influence of early-stage intensive insulin therapy on the plasma levels of vascular endothelial growth factor (VEGF) and the related parameters in patients with severe trauma and the clinical impl
【机 构】
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Emergency Department,the First Affiliated Hospital of PLA General Hospital,Beijing 100048,China
【出 处】
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2013北京协和急诊医学国际高峰论坛
论文部分内容阅读
The influence of early-stage intensive insulin therapy on the plasma levels of vascular endothelial growth factor (VEGF) and the related parameters in patients with severe trauma and the clinical implication were investigated.Sixty-four cases of severe trauma (injury severity score ≥20) with stress hyperglycemia (blood glucose >9 mmol/L) were randomly divided into intensive insulin therapy group and conventional therapy group.ELISA Method,radioimmtmoassay and density gradient gradation one-step process were used to determine plasma VEGF,endothelin-1 (ET-1),and the number of circulating endothelial cells (CECs) at the day of 0,2,3,5 and 7 after admission.
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