【摘 要】
:
Clustering gene expression profiles is important to construeting gene regulatory networks.We consider the problem of clustering short time-course microarray
【机 构】
:
Washington University in St.Louis St.Louis, Missouri, USA
【出 处】
:
The Third IMS-China International Conference on Statistics a
论文部分内容阅读
Clustering gene expression profiles is important to construeting gene regulatory networks.We consider the problem of clustering short time-course microarray data.Direct applications of traditional clustering methods often ignore the temporal ordering of the gene expressions, We instead define candidate gene clusters using the order restriction profiles over the mean expression across time, and convert the clustering problem to a model selection problem.
其他文献
在星河灿烂的流行歌坛,刘薇的名字也许并不耀眼。可听过她唱歌的音乐专家都这样评价:刘薇是个可塑性极强的歌手.她的未来充满希望。刘薇的艺术道路,并非一帆风顺。因而她特
处于社会转型、经济迅速发展时期的通讯企业员工,体验着越来越多的工作压力,也对个体产生了较多的负面影响。因此本文认为,为维护员工身心健康、提高企业效益,引入EAP员工心
2020年中国科学院地理科学与资源研究所建所80周年。回眸80年,从1940年重庆北碚成立的中国地理研究所,到1953年重新组建的中国科学院地理研究所和1956年成立的中国科学院自然资源综合考察委员会,再到1999年地理研究所和自然资源综合考察委员会整合形成现在的地理科学与资源研究所,几经变迁,历经三代人努力,研究所始终如一,求真务实,开拓进取,推动着地理科学与资源科学的创新发展,为国家建设发展和
We propose a new penalty for group variable selection.The purpose of the new penalty is to control the sparsity between groups and within groups.The propose
Several two-stage multiple testing procedures have been proposed to detect geneenvironment interaction in genome-wide association studies (GWAS), though the
It is important to stratify patient population such that the treatment effect is different for different subgroups of patients.The stratification can be use
“女人的名字是弱者,”沙翁的这句话包含了对女性能力的诠释。但作为靖江市农行全辖26个处社中唯一的女主任——长里分理处主任褚秀军,却对这句话感到不服气。她以多年磨炼
许海峰从小生长在一个军人家庭,早识枪支,因此他爱枪。高中毕业后,随社会潮流,他走上上山下乡之路。一天只挣几毛线,他把钱积攒起来,终于买到了一支心爱的气步枪。这是他最
The mortality of ovarian cancer is higher than any other female genital malignant tumors, while there exists strong correlation between early-stage detectio
Functional and longitudinal data are becoming more and more common in practice.This paper focuses on sparse and irregular longitudinal data with a multicate