论文部分内容阅读
Excessive beta(13-35Hz)oscillations have been observed in the basal ganglia of patients with Parkinsons disease(PD).Understanding how beta oscillations originate and can be reduced are important to improve treatments of PD.Using a biophysical model of the cortex-basal ganglia-thalamus network,we first characterize the sensitivity of subthalamic nucleus(STN),globus pallidus externa(GPe)and globus pallidus interna(GPi)beta oscillations to the blockage of different synaptic connections.