Silencing COX-2 by siRNA inhibits the growth of ovarian cancer cells

来源 :2013中国妇产科学术会议 | 被引量 : 0次 | 上传用户：liqingxian1986

【摘要】

：

This study was aimed to investigate the effect of down-regulating the Cyclooxygenase 2 (COX-2) expression on cell proliferation of human ovarian cancer cell.The COX-2 specific short hairpin RNA (shRNA

【作者】

：

LIN Yang CUI Man-hua

【机构】

：

Department of Obstetrics and Gynecology, Second Hospital, Jilin University, Chang chun 130021,China

【出处】

：

2013中国妇产科学术会议

【发表日期】

：

2013年4期

【关键词】

：

ovarian cancer RNA interference COX-2 gene silence

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

右侧入路腹腔镜下肝第Ⅶ、Ⅷ段肿瘤切除15例报告

背景资料1991年Rcich实施了世界首例腹腔镜下肝切除术,随后腹腔镜下肝切除术在全球范围内开展,但是由于技术的限制及手术的巨大风险,总体面言,腹腔镜下肝切除术目前在临床上的推广度并不高,腹腔镜下肝切除术并没有成为像腹腔镜下胆囊切除术一样的常规性手术.

会议

腺病毒介导的碱性成纤维细胞生长因子对老年兔软骨细胞作用的实验研究

目的：观察腺病毒介导的碱性成纤维细胞生长因子对老年兔软骨细胞的增值作用的实验研究.方法：随机将40组培养的老年软骨细胞分成2组,每组20例,其中一组是空白对照组,另一组加入腺病毒介导的碱性成纤维细胞生长因子,分别在培养1天、2天、4天、6天和8天后对两组在酶联免疫检测仪上各个孔光吸收值(OD值)进行测定,进行统计学分析.结果：以MTT法测定所得的OD值作为细胞相对数,软骨细胞生长曲线.Ad-bFG

会议

腺病毒碱性成纤维生长因子兔软骨细胞研究

Environmental risk factors for women of polycystic ovary syndrome in China: a population-based case-

Objectives Polycystic ovary syndrome (PCOS) is a common reproductive endocrinology disease with heterogeneous phenotype.Environmental factors are thought to be involved in the development of PCOS.Pres

会议

Bisphenol Acase control studyendocrine disruptorsenvironmentpolycystic ovary

妊娠期糖耐量受损孕妇胰岛素抵抗和不良妊娠结局的关系

目的分析葡萄糖筛查阳性孕妇胰岛素抵抗与围产结局的关系.方法对南京医科大学第一附属医院产科建卡的单胎孕妇(除外孕前有糖尿病者),对50g葡萄糖筛查试验(glucose challenge test,GCT)阳性者行75g口服葡萄糖耐量试验(OGTT)及胰岛素释放试验,并以此将孕妇分为妊娠期糖尿病(GDM组),妊娠期糖耐量受损(IGT组)和无糖耐量受损(NGT组),OGTT不同时间段分别测定胰岛素

会议

妊娠期糖尿病妊娠期糖耐量异常胰岛素抵抗妊娠结局

Abnormal apoptosis of trophoblastic cells is related to the up-regulation of CYP11A gene in placenta

Background Abnormal placenta trophoblast proliferation and apoptosis is related to the pathogenesis of preeclampsia.Emerging evidence has also indicated that key pregnancy-associated hormones, such as

会议

CYP 11 Apreeclampsiatrophoblastic cellcell proliferationapoptosis

Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines

Background Taxol is a powerful chemotherapy agent that targets the microtubule cytoskeleton, leading to mitotic arrest and cell death; however, its clinical efficacy has been hampered due to the devel

会议

thymidinecell cyclechemoresistanceM stagecell-cycle synchronization

Role of ERα and nuclear receptor on 17α-ethInylestradiol-induced intrahepatic cholestasis in pregnan

Intrahepatic cholestasis of pregnancy (ICP) has been associated with premature delivery and an increased risk for intrauterine fetal distress.It is characterized by pruritus and raised serum bile acid

会议

Cholestasisliverpregnant ratERαestrogenCYPSnuclear receptor

Prospective study of hTERC gene detection by fluorescence in situ hybridization in cervical intraepi

Objective The aim of this study was to evaluate the prognostic significance of hTERC gene overexpression in cervical intraepithelial neoplasia grade 1 (CIN1) natural prognosis.Methods A total number o

会议

fluorescence in situ hybridizationcervical intraepithelial neoplasia 1high ris

The effect of vasopressin injection technique in laparoscopic excision of bilateral ovarian endometr

Objective To evaluate the effects ofvasopressin injection technique in laparoscopic cystectomy on ovarian reserve as determined by base follicle stimulating hormone (FSH) in patients with bilateral en

会议

Endometriosisbilateral endometriomaslaparoscopyOvarian reserveFSH levelVaso

乙肝病毒感染者精液HBV-DNA载量对子代垂直传播的影响

目的探讨乙肝病毒(HBV)感染者精液HBV-DNA的载量对子代垂直传播的影响.方法选择福建省妇幼保健院2009年8月至2011年11月,初次产前检查孕妇血清HBsAg为阴性,其丈夫血清为HBsAg阳性的138个家庭及其新生儿为研究对象.知情同意下收集孕妇血液、丈夫血液及精液,分娩时收集新生儿脐带血,进行HBVM(乙肝病毒血清学标志物)、HBV-DNA检测.以脐带血HBV-DNA载量≥5×102

会议

乙肝病毒载量精液血液垂直传播

Silencing COX-2 by siRNA inhibits the growth of ovarian cancer cells

与本文相关的学术论文