Mutational landscapes distinguish subtypes and prognosis of gastric cancer (壁报交流)

来源 :2015诺贝尔奖获得者医学峰会暨国际肿瘤研究高峰论坛 | 被引量 : 0次 | 上传用户:a12431
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective Gastric cancer (GC) is highly heterogeneous and can be categorized into intestinal and diffuse types, each of which has distinct differentiation status and prognostic outcomes.The aim of study is to gain insight into their molecular differences.Method Delineated the mutational landscapes of two types of GC by deep sequencing of 125 primary tumors and matched normal adjacent tissues.
其他文献
  Objective In previous studies, the associations between BRIP1 (BRCA1-interacting protein 1) polymorphisms and cancer risk were inconsistent.This study was a
会议
  目的 评价肝动脉化疗栓塞(TACE)联合索拉非尼治疗原发性肝癌(HCC)并门静脉癌栓的疗效和安全性。方法 回顾分析2009年10月至2013年10月期间行TACE联合索拉非尼(口服400 mg
会议
  目的 本研究依据内乳前哨淋巴结淋巴引流假说(内乳前哨淋巴结同腋窝前哨淋巴结一样,不仅仅是引流乳腺原发肿瘤区域的前哨淋巴结,也是引流整个乳腺腺体的前哨淋巴结)建立了
  Objective High serum albumin (ALB) and albumin/globulin ratio (AGR) have been reported to be associated with a favorable prognosis for several types of canc
会议
  目的 胃癌患者中普遍存在高血浆纤维蛋白原血症。临床研究认为晚期胃癌患者的血液高凝状态往往与肿瘤的生长和转移密切相关,初治晚期胃癌患者的高纤维蛋白原血症提示预后
  Objective Previous meta-analyses on the association between the ATM rs1801516 polymorphism and breast cancer risk showed conflicting results.We conducted a
会议
  Objective Extranodal NK/T-cell lymphoma, nasal type (ENKL), is a highly aggressive disease with frequent treatment resistance and a poor prognosis.However,
会议
  Objective To investigate whether the expression of heat shock protein 90 (HSP90) is associated with the malignant pheochromocytoma and the effects of HSP90
会议
  Smoking-induced breast cancer formation have been discussed for many years.However, the molecular mechanisms is still uncertained.In this study, reverse-tra
会议
  目的 观察RNA干扰survivin基因对腺样囊性癌移植瘤血管生成的影响.方法 (1)建立腺样囊性癌移植瘤裸鼠模型:随机将Balb/c雄性裸鼠分为6组,每组5只.分组方法为:肿瘤细胞两组(
会议