A practical experimental setup for the speciation of compounds by hydrogen/deuterium exchange(HDX) at atmospheric pressure while performing chromatographic separation is presented.
Circulating Tumor Cells(CTCs) have been demonstrated to be excellent biomarkers for cancer diagnosis and prognosis.During the past ten years,tremendous amounts of effort have been invested in developi
Molecularly imprinted polymers(MIPs) are special type of polymers which have specific imprinting cavities.These imprinted cavities have ability to bind specific target molecules from a complex mixture
Hydrophilic interaction chromatography(HILIC) has attracted increasing attention in recent years.Intensive research has been conducted in the areas of HILIC separation mechanisms,column techniques and
Metastasis is the cause of most cancer deaths in patients with solid tumors.Circulating tumor cells(CTCs) are cancer cells disseminated from primary or secondary tumors that circulate in blood and may
Owing to improper use,slow degradation and bio-accumulation through the food web,organophosphorus pesticides(OPPs) have gradully become a risk and threat to both humans and animals [1].In general,OPPs
Glycoproteins are regulated in protein expression,glycosite occupancy,glycans,glycosite-specific glycans,and glycosite-specific glycan occupancy.Here,we report a comparative analysis of glycoproteins
Comprehensive two-dimensional liquid chromatography(LC×LC) is a crucial technique for the separation of very complex samples of non-volatile molecules and it is virtually indispensable for the separat
Hypertension and hyperlipidaemia are major risk factors for the development of atherosclerosis.Calcium channel blockers(CCBs) have been used for decades and have established antihypertensive effects.
The introduction of HPLC particles with a non-porous core surrounded by a porous shell [1] has initiated intensive research for the reason of the extreme high separation efficiency of these particles.