Materials to Control Biological Cells Functiona Focus on Microtopography Influence

来源 :1st International Conference of Molecular Engineering of Pol | 被引量 : 0次 | 上传用户:fei5301821
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  Surface modifications of materials are used to monitor and evaluate cellular function for several decades.An example of this is the ability to control tissue integration of medical prostheses by changing their composition,surface topography,chemistry,energy,or their mechanical properties.Similarly,control of the surface of materials is also a key element in the effectiveness of diagnostic tools,devices for cell culture,bio-sensors or drug delivery systems.The cells have the ability to discriminate and specifically react to surface characteristics of the materials considered at the micrometer scale as well as the nanometer scale.In this talk,I will focus on the response of cells to topography at their own scale.Our last experience on living cells behavior on microfabricated surfaces with 2D or 2.5D motifs will be detailed.
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