论文部分内容阅读
N-磷酰化氨基酸作为"核酸与蛋白共起源"小分子模型可以发生自组装成肽、成酯、磷上酯交换及磷酰基转位等仿生化反应[1].近年来,磷酰化标记策略被应用于氨基酸、多肽及蛋白质的定性与定量质谱分析.
基于N-磷酰化氨基酸(NPAAs)的手性拆分新策略
【摘 要】
：
N-磷酰化氨基酸作为"核酸与蛋白共起源"小分子模型可以发生自组装成肽、成酯、磷上酯交换及磷酰基转位等仿生化反应[1].近年来,磷酰化标记策略被应用于氨基酸、多肽及蛋白质
【机 构】
：
厦门大学福建省化学生物学重点实验室化学化工学院厦门3610052厦门大学药学院厦门361005厦门大学福建省化学生物学重点实验室化学化工学院厦门3610052;厦门大学药学院厦门361005
【出 处】
：
中国化学会第十届全国磷化学化工学术讨论会暨空间生命起源与进化专委会年会
【发表日期】
：
2015年10期
其他文献
C-H Activation-Based Asymmetric Allylation Reactions Enabled by PalladiumBrnsted Acid Combined Catal
Asymmetric allylation reactions have turned out to be extremely useful in the creation of molecular complexity.1 Both the Pd-catalyzed asymmetric allylic alkyla
会议
Ser-His has been recognized as the shortest peptide with hydrolysis cleavage activity;1 however,its protein cleavage spectrum has not yet been fully explored.He
会议
Copper-Catalyzed Phosphonation-Annulation Approaches to the Synthesis of-Phosphonotetrahydrofurans i
Substituted tetrahydrofuran(THF)and tetrahydropyran(HP)dervatives are important scaffolds in a broad array of biologically active natural compounds,such as lign
会议
Lewis Acid Catalyzed Selective Transformation of 1,3-diarylprop-2-yn-1-ol in the Presence of Diarylp
The attractive feature of allenylphosphorous compounds is diverse reactivity that,with substituent loading capability and axial chirality of the allene unit,mak
会议
设计、合成了有机膦功能化离子液体(3-二乙氧基氧膦基)丙基三苯基膦六氟磷酸盐离子液体 [Ph3 PC3 P(OEt)2][PF6](IL-1),(3-乙氧基苯基氧膦基)丙基三苯基膦六氟磷酸盐离子液体
会议
C-P bond formation reactions utilizing dialkyl H-phosphonates as readily available phosphorus reagents,over the past few decades,have been tremendously were dev
会议
圆二色性是利用不对称分子对左、右圆偏振光吸收的不同来进行分子结构的分析,能为有机化合物的绝对构型、构象和反应机理等提供很多信息.圆二色谱(CD)是研究外源小分子和生物
会议
A.C.Builie等人通过生化反应机理的研究证实了烷基酰基膦酸酯(盐)或次膦酸酯(盐)能使植物致死,正是因为它们对植物丙酮酸脱氢酶系抑制作用的直接结果[1-2].
会议
Synthesis and Fungicidal Activity of(Substituted Phenyl)(Substituted Phenylamino)methylphosphonic Ac
α-Aminophosphonates constitute important motifs among the organophosphorus compounds in medicinal chemistry due to their obvious structural similarities to α-
会议
Direct Oxyphosphorylation of Terminal Alkynyl Acids or Alkynes A Facile Synthesis to β-Ketophosphine
The synthesis of β-ketophosphonates has been achieved through silver-mediated direct oxyphosphorylation of terminal alkynes and H-phosphonates using air as the
会议