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By use of common optical equipment,a laser Michelson interferometer system that can be used for the detection of microfluidic chip is designed.A He-Ne laser beam(power of 0.5mW and diameter of about 0.7mm)is divided into a detection beam and a reference beam with a beam splitter.The reference beam is slightly enlarged with a lens and has a diameter of about 1.5mm.A microfluidic chip with channel diameter of 60μm is placed in the detection arm of the interferometer.