Subgroup analysis has important applications in the analysis of controlled clinical trials.Sometimes the result of the overall group fails to demonstrate that the new treatment is better than the cont
There is increasing acknowledgement of the existence of patient subgroups within clinical research.As a consequence,many clinical trials look to perform subgroup analysis to assess whether a treatment
Stochastic Analysis on a Riemannian manifold is a well developed area in stochastic analysis.We will discuss recent developments on stochastic analysis on a manifold whose Riemannian metric evolves wi
Early biomarkers are often helpful for early efficacy evaluation of clinical endpoints even if the biomarker cannot replace clinical outcome as a surrogate.