• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. TcpC inhibits the phenotypical and functional maturation of dendritic cells

TcpC inhibits the phenotypical and functional maturation of dendritic cells

来源 :浙江省免疫学会第十次学术大会 | 被引量 : 0次 | 上传用户：rudy_luo
【摘 要】
：
Objectives: Toll/interleukin 1 receptor domain containing protein encoded by E.coli (TcpC) was found to be a virulence factor that promotes bacterial survival and is closely related to the pathogenesi
【作 者】
：
Jie Fang Ruiling Chen Xiaoli Xin Yun Zhou Yujie He Dayong Zhang Baoming Wang Sheng Quan Lihuang Zhang Jianping Pan 
【机 构】
：
Department of Clinical Medicine, Zhejiang University City College School of Medicine,Hangzhou 310015
【出 处】
：
浙江省免疫学会第十次学术大会
【发表日期】
：
2016年8期
【关键词】
：
E.coli TcpC Dendritic cells Antigen presentation Pyelonephritis 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Objectives: Toll/interleukin 1 receptor domain containing protein encoded by E.coli (TcpC) was found to be a virulence factor that promotes bacterial survival and is closely related to the pathogenesis of urinary tract infection.It was demonstrated that TcpC can inhibit bactericidal activity of macrophages by blocking toll-like receptor 4 (TLR-4) signaling pathway and plays a crucial role in the pathogenesis of pyelonephritis.The aim of the present study is to examine the regulatory effects of TcpC on the phenotypical and functional maturation of dendritic cells (DC).
其他文献
IL-32及其触发的细胞因子网络在多发性骨髓瘤发生发展中的作用及机制研究
目的：研究IL-32在促进多发性骨髓瘤(MM)骨髓微环境细胞因子网络形成中的作用；并探究该网络对MM细胞生长、耐药、致瘤性等生物学行为的作用和其具体分子机制。方法：RT-PCR、Western blot、流式细胞术检测等检测目的基因及蛋白的表达；MTT和流式细胞术检测细胞增殖、凋亡；Cytokine array以及ELISA检测上清中细胞因子分泌水平。
会议
Uropathogenic Escherichia coli derived TcpC induces apoptosis of human kidney cells
Objectives: To explore the influence of toll/interleukin 1 receptordomain containing protein encoded by E.coli (TcpC) on the apoptosis of kidney cells,so as to provide new evidence to clarify the path
会议
Maltose binding protein promotes dendritic cell maturation
Objectives: Maltose binding protein (MBP),a 42 kDa protein part of the maltose/maltodextrin system of E.coli,is often fused to relevant proteins to promote its yields,facilitate its purification by am
会议
Dendritic cellsMaltose binding proteinE.coliIL-23
Decreased IL-17 during treatment of sputum smear-positive pulmonary tuberculosis due to increased re
Background: Tuberculosis (TB) remains a major public health concern worldwide.Previous studies have demonstrated that IL-17 plays an important role in initial immune response and is involved in both i
会议
IL-17IL-10Regulatory T cellspulmonary tuberculosis
OPN is detrimental to sepsis infected with pseudomonas aeruginosa
Osteopontin (OPN) is a multifunctional protein found in diverse cell types and involved in many pathophysiological process.However,the function of OPN against sepsis infected of pseudomonas aeruginosa
会议
OPNsepsisP.aeruginosa
Regular exercise enhances the immune response against microbial antigens through TLRs
Background/Aims: Regular physical exercise can enhance resistance to many microbial infections.However,little is known about the mechanism underlying the changes in the immune system induced by regula
会议
Regular physical exercisePathogenic infectionCytokineToll-like receptorimmun
Therapeutic Evaluation of Monoclonal Antibody-Maytansinoid Conjugate as a Model of RON-Targeted Drug
Aberrant expression of the RON receptor tyrosine kinase,a member of the MET proto-oncogene family,contributes significantly to pancreatic cancer tumorigenesis and chemoresistance.Here we validate RON
会议
receptor tyrosine kinaseantibody-drug conjugatepancreatic cancerpharmacokinet
Expression of B7-H4 and hepatitis B virus X in hepatitis B virus-related hepatocellular carcinoma
AIM: To investigate the expression and clinical significance of B7-H4 and Hepatitis B virus X (HBx) protein in Hepatitis B virus-related hepatocellular carcinoma (HBV-HCC).METHODS: The expression of B
会议
Hepatocellular carcinomaHepatitis B virusHepatitis B virus XB7-H4Immunohisto
Klebsiella pneumoniae lipopolysaccharides induce TNF-α and IL-1β in macrophages via TLR 4-and 2-denp
Patients infected with Klebsiella pneumoniae are always lead to severe inflammatory response.However,little is known on the host cells pro-inflammatory response to this pathogen.Here we investigated t
会议
Klebsiella pneumoniaelipopolysaccharidesmacrophagespro-infla-mmatory cytokine
Analysis of the immunogenicity and bioactivities of a split influenza A/H7N9 vaccine mixed with MF59
Background: The H7N9 influenza virus caused significant mortality and morbidity in infected humans during an outbreak in China in 2013 and stimulated vaccine development efforts.As previous H7-based v
会议