【摘 要】
：
Aims: Malignant rhabdoid tumours (MRTs) are highly aggressive malignancies of early infancy characterized by inactivation of INI1,a core member of the SWI/SNF chromatin-remodeling complex.The purpose
【机 构】
：
Department of Pathology,Nanjing Jinling Hospital,Nanjing University School of Medicine,Nanjing,China
论文部分内容阅读
Aims: Malignant rhabdoid tumours (MRTs) are highly aggressive malignancies of early infancy characterized by inactivation of INI1,a core member of the SWI/SNF chromatin-remodeling complex.The purpose of this study was to explore the status of multiple key subunits of SWI/SNF complex in MRTs.
其他文献
目的:研究P16蛋白在子宫内膜息肉和子宫内膜增生症中的表达,探讨P16蛋白在子宫内膜息肉和子宫内膜增生症鉴别诊断中的价值.方法:收集43例子宫内膜息肉和37例子宫内膜增生的存档蜡块,应用免疫组织化学EnVision法检测上述标本中P16蛋白的表达.结果:P16在子宫内膜息肉间质细胞中阳性表达率为91％,而在子宫内膜增生间质中不表达,二者之间有明显差异(P＜0.01);P16蛋白在子宫内膜息肉和子宫
目的:探讨子宫颈腺癌的临床与病理形态学特征.方法:对我院2002年到2013年间收诊的14例的临床与病理资料进行回顾性研究分析,并复习文献,就其临床特点、病理形态学特征、免疫及组织化学表型进行探讨.结果:临床常表现为粘液性白带增多或不规则少量出血,宫颈肥大或糜烂,可无明显症状.组织形态上,常常是高分化的腺体伴有粘液分泌,粘液可渗入到间质.CEA高表达,爱先蓝与PAS染色阳性.结论:子宫颈腺癌,诊断
目的:探讨中肾管附件肿瘤的临床病理特征、免疫表型、鉴别诊断、治疗及预后,以提高对中肾管附件肿瘤的认识,减少误诊及漏诊.方法:对本院收治的中肾管附件肿瘤病例进行临床和病理学观察、免疫表型研究并复习相关文献.结果:中肾管附件肿瘤好发于18-83岁(平均50岁)的女性患者.无特异的临床表现.巨检:肿瘤常单侧发生,平均直径6.1cm;肿瘤界限清楚,切面灰白、灰红色,质中等或脆,可有囊腔及坏死.镜检:肿瘤细
In this study,we reported the first PEComa arising within the cervix with TFE3 gene rearrangement and aggressive biological behavior.Morphologically,the tumor showed infiltrative growth into the surro
目的:探讨子宫苗勒氏腺肉瘤伴性索样分化临床病理学特征、免疫表型、诊断和鉴别诊断.方法:对1例子宫苗勒氏腺肉瘤伴性索样分化进行HE染色、免疫组化染色,并复习相关文献.结果:患者女性,56岁,临床表现为绝经后阴道出血.大体上,肿瘤位于宫腔内,呈一大小约7cmx4cmx3cm灰白色肿物,突向宫腔,切面灰红灰白色,肿物基底部与子宫肌层界限尚清.组织学上,肿瘤均由良性腺体和富于细胞的间叶成分组成.良性腺体为
Esophageal cancer was recorded as the fifth most commonly diagnosed cancer and the fourth leading cause of cancer-related death in China in 2009.Esophageal squamous cell carcinoma (ESCC) accounts for
目的:探讨穿刺活检标本中前列腺梭形细胞病变的鉴别诊断及前列腺原发性胃肠道间质肿瘤的临床病理特征.方法:复习1例前列腺穿刺活检诊断胃肠道间质肿瘤标本的HE切片、免疫组化染色切片、患者的临床资料及相关文献.结果:男性64岁患者,因排尿时下腹部疼痛一年余,且逐渐加重入院,核磁共振检查示前列腺占位,考虑前列腺癌的可能.直肠指检示前列腺大小约三横指,质韧,表面光整,可触及明显结节,中央沟消失.血PSA为1.
We report a case of 3 1-year-old woman with diffuse sclerosing hemangiomas (SH) in the right lung.A computed tomography (CT) of the chest showed diffuse well-defined nodules in the right lobes of the
Mesenchymal chondrosarcoma is a rare aggressive neoplasm typically affecting the bones of young adults.It may also arise in somatic soft tissue,the CNS and other organs.We report a case of mesenchymal
时隔6年,新版的《Enzinger&Weisss软组织肿瘤》一书终于面世,仍由Sharon W.Weiss等主编.依据近年来对软组织肿瘤的新认识,本书的内容做了一系列调整.在新版中删除了间皮肿瘤、副神经节瘤及神经母细胞瘤3个章节.这类肿瘤虽然可以发生于软组织(包括腹膜后),但是它们的组织起源却不是间叶源性,从而保证了书本内容的一致性.为了方便读者阅读与理解,作者把伴有黑色素细胞分化的软组织肿瘤归为