Intragenomic heterogeneity of 16S rRNA genes causes overestimation of prokaryotic diversity

来源 :The 13th International Conference on Culture Collections(ICC | 被引量 : 0次 | 上传用户：leegimars

【摘要】

：

　　Ever since Carl Woese introduced the use of 16S rRNA genes for determining the phylogenetic relationships of prokaryotes, this method has been regarded as t

【作者】

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Dong-Lei Sun Xuan Jiang Qinglong L.Wu Ning-Yi Zhou

【机构】

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KeyLaboratoryofAgriculturalandEnvironmentalMicrobiology,WuhanInstituteofVirology,ChineseAcademyofSci

【出处】

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The 13th International Conference on Culture Collections(ICC

【发表日期】

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2013年9期

【关键词】

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Intragenomic heterogeneity 16S rRNA gene prokaryotic diversity

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　　Ever since Carl Woese introduced the use of 16S rRNA genes for determining the phylogenetic relationships of prokaryotes, this method has been regarded as the "gold standard" in both microbial phylogeny and ecology studies.However, intragenomic heterogeneity within 16S rRNA genes has been reported in many investigations and is believed to bias the estimation of prokaryotic diversity.

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Intragenomic heterogeneity of 16S rRNA genes causes overestimation of prokaryotic diversity

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