【摘 要】
：
A series of perylenediimide-cored dendrimers with different generations via "click" reaction are synthesized [1].These dendrimers display exceptional chemical, thermal, photochemical stability with hi
【机 构】
：
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology,Bei
【出 处】
：
2013 International Symposium on Integrated Molecular / Mater
论文部分内容阅读
A series of perylenediimide-cored dendrimers with different generations via "click" reaction are synthesized [1].These dendrimers display exceptional chemical, thermal, photochemical stability with high fluorescence quantum yields.The aggregation of the encapsulated PDI chromophores is noticeably suppressed by outer cationic dendrimers, thus leading to the enhancement of optical performances in water.In addition, to investigate the ability of these dendrimers to enter into live cells, Drosophila S2 cells are incubated with these dendrimers.All cationic dendrimers (G1, G2, and G3) could rapidly internalize into live cells with high efficacy of gene transfection.The highest cellular uptake ability and transfection efficacy of G3 is explained by bigger outer branches and more positive charges [2].Cell-uptake experiments show that the cellular uptake ability and the transfection efficacy of dendrimers increase with increasing dendrimers generation.
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