Real time visualizing and tracing of HSV-TK/GCV suicide gone by quantum dots

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：liuhu1314518

【摘要】

：

【作者】

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Xuanang Xiao Dan Shao Zheng Wang Yue Pan Li Chen Jing Li

【机构】

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Department of Pharmacology,Norman Bethune Medical College,Jilin University,126 Xin Min Street,Changc

【出处】

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International Conference on Nanoscience & Technology,China 2

【发表日期】

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2013年3期

【关键词】

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Quantum dots Herpes simplex virus thymidine kinase Real time Gene therapy

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　　Among various cancer gene therapy approaches, suicide gene therapy seems to be an effective system characteristic with the unique bystander effects.In this work, real time visualizing and tracing of HSV-TK/GCV suicide gene system by quantum dots was carried out by using the developed QD-TK conjugates, which is constituted by the plasmid TK covalent linkage to carboxylate group on the surface of QDs.

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Real time visualizing and tracing of HSV-TK/GCV suicide gone by quantum dots

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