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In this study,Combined Anaerobic-Anoxic-Aerobic reactors(CAnA)were used to treat the Idebenoneproduction pharmaceutical wastewater.After 70 days domesticated,the CAnA process could effectively degradethe pollutants in the wastewater with 600 ml CH4/Day recovered in the Up-flow Anaerobic Sludge Bed(UASB).The maximum COD removal rate was 96%at an Organic Load Rate(OLR)of 3 g/(L d).