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  5. The study of N-succinyl chitosan-poly-L-lysine-palmitic acid triblock polymer micelle for co-deliver

The study of N-succinyl chitosan-poly-L-lysine-palmitic acid triblock polymer micelle for co-deliver

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：nxf_2004_0
【摘 要】
：
Background: It is the hot issue that targeting therapy and reversing multidrug resistance are used to improve therapeutic effect and reduce side effect.Combination of two or more therapeutic approache
【作 者】
：
Chun-ge Zhang Wen-Jing Zhu Xue-nong Zhang 
【机 构】
：
Department of Pharmaceutics,College of Pharmaceutical Sciences,Soochow University,Suzhou 215123,Peop
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
【发表日期】
：
2014年8期
【关键词】
：
Multidrug resistance Doxorubicin siRNA Synergistic tumor therapy 
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Background: It is the hot issue that targeting therapy and reversing multidrug resistance are used to improve therapeutic effect and reduce side effect.Combination of two or more therapeutic approaches with different mechanisms is a promising strategy for effective treatments of cancers with synergistic or combined effects.Co-delivery of siRNA and chemotherapeutic agents within a single nanoparticle has been developed to combat multidrug resistance in cancer therapy.
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