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Background Peripheral-blood (PB) and bone marrow (BM) are both widely used in hematopoietic stem cell transplantation (HSCT).However, it has been controversial whether the use of PB or BM leads to a more favorable outcome of HSCT that involves unrelated HLA-matched donors.Methods We searched PubMed and Medline for relevant articles.Risk ratio (RR) and 95% confidence intervals (CIs) were calculated for statistical analyses.