Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomyc

来源 :全国卫生毒理学术研讨会 | 被引量 : 0次 | 上传用户：wumingwuming2009

【摘要】

：

【作者】

：

Hui Zhao Qing-Qing Wu Lin-Feng Cao Hou-Ying Qing Cheng Zhang Yuan-Hua Chen Hua Wang Rong-Ru Liu De-Xiang Xu

【机构】

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Department of Toxicology,Anhui Medical University,Hefei,China

【出处】

：

全国卫生毒理学术研讨会

【发表日期】

：

2014年9期

【关键词】

：

melatonin bleomycin pulmonary fibrosis endoplasmic reticulum stress unfolded pro

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　　Several reports indicate that melatonin alleviates bleomycin (BLM)-induced pulmonary fibrosis in rodent animals.Nevertheless,the exact mechanism remains obscure.The present study investigated the effects of melatonin on endoplasmic reticulum (ER) stress and epithelial-mesenchymal transition (EMT) during BLM-induced lung fibrosis.

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