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Objective Platycarya Strobilacea Sieb.et Zucc alcohol extracts(PSZ) inhibited the proliferation and induced accumulation of large phase-lucent cytoplasmic vacuoles in human nasopharyngeal carcinoma(NPC) CNE1 and CNE2 cells,and finally lead to cell death.We suppose PSZ induced a new cell death which previously described as "Methuosis".