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Anovelmulti-componentscaffoldscontainingPLGA,hydroxyapatite(HA)bonemorphogeneticprotein-2(BMP-2)andchitosanwerepreparedforbonetissueengineering.Themulti-componentscaffoldsshowedporousstructurebymodifiedmethodusingiceaspore-foamingagent,andchitosanwasmodifiedontothesurfaceofscaffolds.