Objective:One stage repair of interrupted aortic arch (IAA) associated cardiac anomalies in neonates and infants is a big challenge for whole surgical team.Deep hypothermic circulatory arrest prolongs myocardial ischemia and might induce cerebral and major organs dysfunction.We reviewed the perfusion experiences of 13 cases with a modified technique of regional cerebral perfusion under deep hypothermic circulatory arrest (DHCA) during one stage repair of IAA in infants.