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  5. Core-shell hybrid upconversion nanoparticles carrying stable nitroxide radicals for upconversion lum

Core-shell hybrid upconversion nanoparticles carrying stable nitroxide radicals for upconversion lum

来源 :The 6th International Conference on Nanoscience and Technolo | 被引量 : 0次 | 上传用户：lxlove584
【摘 要】
：
Purpose: Nitroxide radicals, such as 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO) and its derivatives, have been paid attention as contrast agents for magnetic resonance imaging (MRI) and electron par
【作 者】
：
Chuan Chen Ning Kang Lei Ren 
【机 构】
：
The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation,State Key Laboratory of Physi
【出 处】
：
The 6th International Conference on Nanoscience and Technolo
【发表日期】
：
2015年5期
【关键词】
：
Nitroxide radicals upconversion nanoparticles dual-modality imaging 
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　　Purpose: Nitroxide radicals, such as 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO) and its derivatives, have been paid attention as contrast agents for magnetic resonance imaging (MRI) and electron paramagnetic resonance imaging (EPRI). However, due to the rapid one-electron bioreduction to diamagnetic N-hydroxy species, Nitroxide radicals has limited their use in in vivo applications. Methods: a new approach of silica coating for carrying stable radicals was prepared.
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