【摘 要】
：
Baekground The aim of this study was to identify whether a stem cell biomarker, KLF4, may predict the pathological complete remission to neoadjuvant chemotherapy for patients with locally advanced bre
【机 构】
：
Department of Surgical Oncology, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine,
【出 处】
：
2015浙江省肿瘤外科学术年会暨首届钱江国际肿瘤外科高峰论坛
论文部分内容阅读
Baekground The aim of this study was to identify whether a stem cell biomarker, KLF4, may predict the pathological complete remission to neoadjuvant chemotherapy for patients with locally advanced breast cancer.Methods We identified 12 locally advanced breast cancer patients who achieved pathological complete remission(pCR)after neoadjuvant chemotherapy and for each, we selected three non-pCR breast cancer patients, who werematched for age, clinical TNM stage and neoadjuvant chemotherapy cycles.
其他文献
本文选取明代医家岳甫嘉《妙一斋医学正印种子编》种子验案之一,并其附方六首,评析其诊治思路,选方思路,用药思路的核心为从脾肾论治种子,提出对当前男子不育症中医辨证治疗的临证启示脾肾相关与男性生殖密切相关:调精种子,要关注脾肾先后天之本;调精种子,要关注精与气血之关系;调精种子,要关注补肾补脾之先后序贯.
在人类社会繁荣发展的今天,当代人的不孕不育发病率也随着社会的发展与日俱增,当然,这绝对不是一个好现象.而我国古代医学典籍从防治未病,养生等方面的论述,对于不孕不育的预防和治疗也起了很好的指导作用.黄帝内经,成书与两汉之际,是我国医学史上的巨著. 他不仅确立了中医基本理论体系,同时其中也包含了不少关于不孕不育方面的相关论述.快节奏的都市生活，不合理的饮食习惯，作息习惯，来自各方的无形的压力，使得很多
本文经多年临床治疗研究并总结了影响优生优育造成出生缺陷的主要原因及因素:1.未婚或已婚,曾有人工流产或药物流产史者;2.有上节育环或服避孕药史者;3.未采取任何节育措施而有自然流产史者.并针对性地应用《内经》治未病的科学思想,创立"中医妇科分步疗法".即第一步,经前辨寒热虚实,使经血应期而至;第二步,经期动静结合,因势利导,以调经和血清宫为要;第三步,经净三日,补血益精,以培生殖之本;第四步,节情
目的：探讨miR-130b在人肝细胞癌(HCC)中的表达、与临床病理特征的关系及可能机制.方法：用实时定量PCR(qRT-PCR)检测miR-130b在86例HCC及癌旁组织、不同肝癌细胞系的表达;免疫组织化学染色检测miR-130b不同表达水平的HCC组织中上皮型钙黏素(E-cadherin)、波形蛋白(vimentin)及过氧化物酶体增殖物激活受体γ(PPARγ)的表达情况;qRT-PCR检测
Long noncoding RNAs (lncRNAs) play crucial roles during cancer occurrence and progression.However,there are still many unknown relationships between the IncRNA expression levels and hepatocellular car
Background Spleen preservation (SP) is beneficial for patients undergoing distal pancreatectomy of benign and borderline tumors; however, the conventional laparoscopy approach is less effective in pre
恶性肿瘤的发病率呈逐年上升趋势，已成为临床中最常见疾病之一。随着损伤控制外科概念不断深入人心，肿瘤的治疗也进入了微创时代。患者不仅要求治愈肿瘤，而且要求尽量手术疤痕小且美观，因此寻找安全可行又能达到美容效果的治疗方式成为临床医生探索的目标。在超声、CT等介质手段引导下经皮穿刺肿瘤射频消融技术作为一种新的治疗方法，具有微创、无疤痕、最大限度的保留原有脏器功能、疗效显著等优点。我院自开展肝脏肿瘤射频消
To investgate the correlation between expression of BH3-only proteins (PUMA and BIM) and clinical outcome of colorectal cancer (CRC) patients administrated with oxaliplatin-based chemotherapy.Experime
The main purpose of this study is to investigate the interactions between Lin28 and Her2 in gastric cancer.Methods Lin28 and Her2 expression were evaluated in surgically resected samples of 298 gastri
Background Targeted therapies are emerging treatment options for gastric cancer (GC).Patient-derived tumor xenograft(PDTX) models of GC closely retain the features of the original clinical cancer, off