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5. Synthesis and Process Optimization of Antitumor Agent NVP-BEZ235

Synthesis and Process Optimization of Antitumor Agent NVP-BEZ235

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：hdjc1314

【摘 要】

：

Aims:NVP-BEZ235 is the development of a Novartis ATP competitive inhibition of PI3K/mTOR anticancer drug and inhibition the catalytic activity of Akt and mTOR.This paper introduces the research progre

【作 者】

：

F.L Y.B.TU M.WANG W.H.WANG P.W.ZHENG W.F.ZHU 

【机 构】

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School of Pharmacy,Jiangxi Science & Technology Normal University,Nanchang 330013,China

【出 处】

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2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

PI3K/mTOR inhibitor NVP-BEZ235 Industrialization Synthesis 

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　　Aims:NVP-BEZ235 is the development of a Novartis ATP competitive inhibition of PI3K/mTOR anticancer drug and inhibition the catalytic activity of Akt and mTOR.This paper introduces the research progress of small molecule inhibitors of anti-tumor.

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