2. 您的位置
3. 首页
4. 会议论文
5. Self-programmed pH-sensitive polymeric prodrug micelle for synergistic cancer therapy

Self-programmed pH-sensitive polymeric prodrug micelle for synergistic cancer therapy

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：anewday4all

【摘 要】

：

Chemotherapy plays an important role in the treatment of cancer,but the optimal clinical approach for chemotherapy has not been well established [1].As an emerging approach,the synergistic anticancer

【作 者】

：

Ying Zhang Linghui Chen Jianxun Ding Kexin Shen Modi Yang Chunsheng Xiao Xiuli Zhuang Xuesi Chen 

【机 构】

：

Key Laboratory of Polymer Ecomaterials,Changchun Institute of Applied Chemistry,Chinese Academy of S

【出 处】

：

The Third Symposium on Innovative Polymers for Controlled De

【发表日期】

：

2014年6期

【关键词】

：

bortezomib pH-responsive protocatechualdehyde synergistic anticancer 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Chemotherapy plays an important role in the treatment of cancer,but the optimal clinical approach for chemotherapy has not been well established [1].As an emerging approach,the synergistic anticancer drug delivery exhibits promising prospects to overcome the chemotherapy resistance and optimize the therapeutic program.

其他文献

Targeted CT imaging of cancer cells using PEGylated low-generation dendrimer-entrapped gold nanopart

As a powerful molecular imaging technology,computed tomography (CT) is able to be used for cancer cell imaging in vitro and in vivo with the assistance of contrast agents.To form effective nanoscale C

会议

PAMAM dendrimersgold nanoparticlescomputed tomographyliver cancer cells

Hyaluronic acid based injectable hydrogels for localized and sustained gene delivery

Polymer based gene delivery systems have been widely studied for their safety and simple preparation compared with viral gene carriers [1].However,in most cases the polymer based gene carriers could o

会议

hyaluronic acidinjectable hydrogelsustainedgene delivery

X-ray CT detection and photo ablation of metastatic positive lymph node with HER-2 targeting W18O49

Breast cancer is the leading cause of cancer death in females [1],and metastasis of this malignancy attributes mainly to the death.Investigations have shown that metastasis occurs mostly through the l

会议

breast cancermetastasisphotothermal therapyHER-2W18O49

Novel microcapsules for drug and gene delivery

Layer-by-layer self-assembly technology exploiting template has been used to effectively transfer genes into cells or administer protein drugs into the body without damaging the gene and drugs activit

会议

Layer-by-layer microcapsulespolyethyleniminepoly(acrylic acid)templates

Co-delivery of poly I:C and STAT3 siRNA by nanovaccines effectively overcomes tumor-associated dendr

Although therapeutic vaccines have emerged as a promising strategy for cancer immunotherapy,their therapeutic efficacy is often dampened by tumor-associated dendritic cell (TADC) dysfunction,which can

会议

nanovaccinePoly I∶CSTAT3 siRNAtumor-associated dendritic cells

Preparation of fluorescent core/shell nanoparticles from amphiphilic cellulose-based copolymers for

Cellulose-based self-assembled micelles have emerged as a new generation of value-added fimctional nanostructures that have been develop from green and cheap materials from biomass resources.In our pr

会议

fluorescentcellulose-basedp-dioxanonenanomicellescell imaging

Phospholipid-like amphiphilic polymer conjugate micelles for on-demand intracellular curcumin delive

The tumour tissue is characteristic of an acid-microenvironment (pH~6.8).This feature as well as the low pH milieu (4.5-6.5) of endosome and lysosome provides an excellent in situ trigger for ondemand

会议

acid-responsiveself-assemblymicelleconjugatecurcumin

Combinatorial synthesis and high throughput screening of lipidoids for gene delivery

Cationic lipidoids have potential applications in the field of gene delivery due to their unique properties.We use combinatorial chemistry to synthesize libraries of thioether lipids that are composed

会议

cell transfectionlipidoidgene deliverycombinatorial chemistry

pH-responsive supramolecular prodrug micelles based on cucurbit[8]uril for iutracellular drug delive

In recent years,cucurbit[8]uril (CB[8]) has been widely employed as a linking motif to prepare various kinds of supramolecular assemblies for biomedical applications due to the fact that CB[8] is capa

会议

pH responsivecucurbit[8]urilprodrug micelleshost-guest interactions

cRGD-functionalized AuNR-cored PEG-PCL nanoparticles for efficacious glioma chemotherapy

The current micellar drugs suffer a lot from low in vivo stability,premature drug release,inefficient tumor cell uptake,as well as slow drug release in the tumor site and inside the tumor cells,which

会议

cRGDgold nanorodlight-sensitivecontrolled drug releaseglioblastoma