基于纳米编码的DNA分子超灵敏检测

来源 :中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议 | 被引量 : 0次 | 上传用户：huiyuanai852

【摘要】

：

疾病的早期诊断，尤其是恶性肿瘤的早期诊断对提高其预查能力、降低其死亡率等都具有重要意义。疾病的早期诊断需要检测微量甚至痕量的生物大分子包括某些特定序列的DNA 分子等。纳米技术作为一项备受关注并且具有无穷潜力的新兴技术，可以与疾病的早期检测技术结合，用于疾病的检测和诊断且具有灵敏、准确、快速、简便等特点。本文介绍一种通过将靶DNA 分子与金纳米棒1：1编码并在暗场显微镜下对金纳米棒进行精确计数进而

【作者】

：

吴振杰李国花孙树清

【机构】

：

清华大学深圳研究生院光学检测与成像实验室,深圳市南山区西丽大学城清华校区D栋,518055;清华大学物理系,清华大学物理系,北京市海淀区理科楼,100084

【出处】

：

中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议

【发表日期】

：

2016年5期

【关键词】

：

早期诊断金纳米棒磁珠暗场成像精确计数超灵敏检测

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基于纳米编码的DNA分子超灵敏检测

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