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Objectives To investigate the value of colour Doppler echocardiography (CDE) in occlusion of elderly with atrial septal defect (ASD).Methods In total of 64 cases of elderly ASD, observe the location, size and residual edge using two-dimensional echocardiography (2DE), observe the atrial septal colourful shunt bunch flow signal and the heart valve colourful regurgitation bunch flow signal using colour Doppler flow imaging (CDFI) and measure the pulmonary artery pressure using continuous Doppler (CW) before the occlusion.