【摘 要】
：
Objective: To evaluate the prognostic value of E-cadherin,β-catenin, vimentin, and S100A4 expression in a cohort of squamous cell lung carcinoma (SqCC) patients.Methods: Tumors from 204 patients with
【机 构】
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Department of Lung Cancer,Cancer Institute and Hospital of Tianjin Medical University,Tianjin,China
【出 处】
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22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会)
论文部分内容阅读
Objective: To evaluate the prognostic value of E-cadherin,β-catenin, vimentin, and S100A4 expression in a cohort of squamous cell lung carcinoma (SqCC) patients.Methods: Tumors from 204 patients with surgically resected SqCC were used for the immunohistochemical analyses ofE-cadherin, β-catenin, vimentin, and S100A4 expression.The chi-squared test was used to analyze the correlation between the expression of these markers and clinicopathologic parameters.The Kaplan-Meier method and log-rank test were used to calculate OS and DFS.A prognostic analysis was conducted using univariate and multivariate Cox regression models.The chi-squared test for linear trends was applied to evaluate the correlations between the expression of E-cadherin, β-catenin,vimentin, and S100A4.
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