【摘 要】
：
Mesenchymal stem cells (MSCs) have been extensively investigated to treat a wide range of diseases due to their easy accessibility, high self-renewal capacity, low immunogenicity, and free of ethical
【机 构】
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State Key Laboratory of Natural Medicine, Department of Pharmaceutics, China Pharmaceutical Universi
【出 处】
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2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会
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Mesenchymal stem cells (MSCs) have been extensively investigated to treat a wide range of diseases due to their easy accessibility, high self-renewal capacity, low immunogenicity, and free of ethical issues.More importantly, inflammatory tissues tropism renders them as a promising tumor-targeted delivery vesicle.Currently, genetic engineering is the major strategy in MSCs-mediated cancer therapy.However,using viral vectors for transfection of MSCs can lead to unwanted transformation and significantly increase the risk of secondary malignancies.
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