【摘 要】
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As a complex disorder, PCOS (polycystic ovary syndrome) is present with heterogeneous characteristics originating from the combined effect of both environmental and genetic factors.On the genetic aspe
【机 构】
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Centre for Reproductive Medicine,Shandong University;Renji Hospital,Shanghai Jiao Tong University Sc
【出 处】
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2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议
论文部分内容阅读
As a complex disorder, PCOS (polycystic ovary syndrome) is present with heterogeneous characteristics originating from the combined effect of both environmental and genetic factors.On the genetic aspects, a series of family and twin studies have demonstrated the heritable nature of PCOS.Meanwhile, several researchers have tried to find the link between certain genes and PCOS.Recently, the whole-genome association studies (GWASs) of PCOS provide more reliable and unbiased results and represent a milestone for genetic studies in PCOS.However, the greatest challenges to explore the functional consequences of the GWAS susceptibility loci are just in the front.
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