Long noncoding RNA H19 inhibits the proliferation of fetal liver cells and the Wnt signaling pathway

来源 :第十四次全国医学遗传学学术会议 | 被引量 : 0次 | 上传用户：yanzhenwei2

【摘要】

：

　　Long noncoding RNA (IncRNA) H19 is the first imprinted IncRNA to be defined.H19 has been implicated in the development of the liver, as H19 is the most diff

【作者】

：

王少冰;袁继行;杨富;刘岩;周传传;刘峰;马金召;孙树汉;王芳;

【机构】

：

第二军医大学基础部医学遗传学教研室上海200433

【出处】

：

第十四次全国医学遗传学学术会议

【发表日期】

：

2015年期

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　　Long noncoding RNA (IncRNA) H19 is the first imprinted IncRNA to be defined.H19 has been implicated in the development of the liver, as H19 is the most differentially expressed IncRNA in liver development according to our previous microarray results;however, the function of H19 and its underlying mechanism of action are largely unknown.In this study, we found that H19 was overexpressed in fetal liver tissues and that H19 inhibited the proliferation of fetal liver cells.

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Long noncoding RNA H19 inhibits the proliferation of fetal liver cells and the Wnt signaling pathway

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