The effects and mechanism of miR155 on thefibroblasts-to-myofibroblasts transition in dermal fibrobl

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  Hypertrophic scar, which is a troublesome problem in the field of tissue repairthat urgently need to be solved.Present study confirmed that TGF-β 1 inducedmyofibroblasts transition is the key mechanism that contributing to thepathogenesis of hypertrophic scar.
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Hypertrophic scar (HS) is a serious skin fibrotic disease characterized by excessive hypercellularity proliferation and extracellular matrix (ECM) component deposition.
Coxsackie and adenovirus receptor (CAR), a cell adhesion molecule of the immunoglobulin superfamily, is predominantly localized to cell-cell contacts between epithelial and endothelial cells.
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Hypertrophic scarring (HS) is a serious fibrotic skin condition, there is currently no satisfactory therapy to treat the disease, largely due to the undefined molecular mechanism.
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Hypertrophic scar (HS) is characterized by the overgrowth of fibroblasts and often considered as a kind of benign skin tumor, thus chemotherapeutic drugs have been used to treat HS.
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The coxsackie and adenovirus receptor (CAR) is a cell adhesion molecule belonging to the immunoglobulin superfamily and is predominantly localized to cell-cell contacts between epithelial and endothel
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Introduction Many burn injury patients, claiming the history of psychiatric disorders, do not meet sufficient mental health care.These problems are more serious in China, which is a developing country
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Background: Although burn injury remains one of the most devastating ordeals for the human being, little has been reported on the individual patients perception about the burn experience in the Chines
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目的 初步验证吲哚胺2,3-双加氧酶(IDO)在BMSCs对初始CD4+T细胞向Th 17/Treg细胞分化的影响及其可能机制.方法 分离培养Balb/c小鼠来源的BMSCs,以Balb/c小鼠脾脏来源的CD4+T细胞为反应细胞,以丝裂霉素预处理过的C57BL/6小鼠脾脏细胞作为刺激细胞.实验分为3组:对照组,刺激细胞+反应细胞;BMSCs组,刺激细胞+反应细胞+BMSCs;IDO拮抗组,刺激细胞