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A water-soluble polysaccharide was isolated from the leaves of Cyclocarya paliurus (Batal.) Iljinskaja,a well-known native healthy tea in China.The process of isolating and purifying the polysaccharide was achieved through gel permeation chromatography.The hypoglycemic effect of a water-soluble polysaccharide was investigated by using the model of both normal healthy and alloxan-induced diabetic rats.