柞蚕βGRP识别机制的研究

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:lutiaotiao
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在先天性免疫系统中,不同的模式识别蛋白(Pattern recognition proteins,PRPs)对不同的病原体相关分子模式(Pathogen-associated molecular patterns,PAMPs)/病原菌具有普遍或特异性识别作用,是启动先天性免疫系统进而产生信号传导的"开门砖",并最终产生有效的防御反应.其中,特异性识别真菌特有PAMP-1,3-β-D-葡聚糖的PRR称为1,3-β-D-葡聚糖识别蛋白(1,3-β-D-glucan recognition protein,βGRPs),是昆虫先天性免疫系统中最重要的PRRs之一.
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