中药安肠愈疡汤对溃疡性结肠炎大鼠结肠组织中TFF3、MUC2及TLR4基因表达的影响

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:cherrydarling
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  背景:TLR4是介导免疫和炎症反应的主体,TFF3、MUC2为肠粘膜保护因子,维持肠粘膜屏障功能。目的:观察中药复方安肠愈疡汤对溃疡性结肠炎(UC)大鼠结肠组织中TFF3、MUC2及TLR4基因表达的影响,以探讨其作用机制。方法:将90只SPF级Wistar大鼠随机分为空白对照组、模型对照组、安肠愈疡汤低、中、高剂量组和美沙拉嗪组。
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