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  5. Ovariectomy-induced osteoporosis influences the middle and late periods of bone healing in a mouse f

Ovariectomy-induced osteoporosis influences the middle and late periods of bone healing in a mouse f

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户：reap
【摘 要】
：
Background: It is known that bone healing was delayed in the presence of osteoporosis in humans.However, due to the complexities of the healing of osteoporotic fractures, animal models may be more app
【作 者】
：
Jian Pang Meina Ye Hailing Guo Xiang Wang Cao Yuelong Yuxin Zheng Yuanchuan Chen Yongfang Zhao Hongsheng Zhan Yinyu Shi 
【机 构】
：
Research Institute of Orthopaedics, Shuguang Hospital Affiliated to Shanghai University of Tradition
【出 处】
：
第七届国际骨质疏松及骨矿盐疾病学术会议
【发表日期】
：
2014年3期
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Background: It is known that bone healing was delayed in the presence of osteoporosis in humans.However, due to the complexities of the healing of osteoporotic fractures, animal models may be more appropriate to study the effects of osteoporosis in more details and to test drugs on the fracture repair process.The purpose of this study was to investigate the influence of ovariectomy-induced osteoporosis in bone healing in an open femoral osteotomy model, and to test the feasibility of this model for evaluating the healing process under osteoporotic conditions.
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