【摘 要】
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Marine actinomycetes are novel sources for the discovery of bioactive compounds.In the previous studies, we have isolated Streptomyces xinghaiensis NRRL B24674T
【机 构】
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SchoolofLifeScienceandBiotechnology,DalianUniversityofTechnology,Dalian116024,China
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Marine actinomycetes are novel sources for the discovery of bioactive compounds.In the previous studies, we have isolated Streptomyces xinghaiensis NRRL B24674T from marine sediment sample collected from Xinghai Bay Dalian, China, about 10 m below the sea level,and identified it to be a novel species of the genus Streptomyces.The draft genome sequence of S.xinghaiensis was accomplished (Journal of Bacteriology 193: 5543) and genome mining of S.xinghaiensis has led to the discovery of novel antibiotics against drug resistant bacterial pathogens (unpublished data).In this study, a marine-derived Streptomyces strain M10, which exhibited good activity against pathogenic fungal strain Candida albicans, was subjected to genome mining.Analysis of the 16S rRNA sequence of M10 indicated that it is most closely related to S.
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