论文部分内容阅读
Introduction: Vascular calcification (VC) is the major risk factor for cardiovascular mortality in chronic renal failure (CRF) patients, but the pathogenesis remains largely unknown and effective therapeutic targets are urgent to be explored.The Immediate Early Gene X-1 (IEX-1) plays a role in controlling cellular growth and differentiation.As IEX-1 expressed in the cartilage tissue and it can modulate protein phosphatase, we aimed to study whether IEX-1 affects VC.