【摘 要】
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Objective Cigarette smoke may contribute to pulmonary vascular remodeling that resulted by pulmonary artery smooth muscle cell proliferation before pulmonary hypertension in chronic obstructive pulmon
【机 构】
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Department of Respiratory and Critical Care Medicine,Tongji Hospital of Tongji Medical College, Huaz
【出 处】
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中华医学会呼吸病学年会——2013第十四次全国呼吸病学学术会议
论文部分内容阅读
Objective Cigarette smoke may contribute to pulmonary vascular remodeling that resulted by pulmonary artery smooth muscle cell proliferation before pulmonary hypertension in chronic obstructive pulmonary disease.Activated extracellular signal-regulated kinases 1 and 2 (ERK1/2) is considered to participate in this procession.This study is investigated the potential role of ERK1/2 in rat pulmonary artery smooth muscle cells (rPASMCs) proliferation and pulmonary vascular remodeling induced by cigarette smoke.
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