Robenacoxib is a newer non-steroidal anti-inflammatory drug(NSAID) and effective for the management of perioperative pain and inflammation.A preoperative administration of robenacoxib is approved in many countries.The preoperative administration of NSAIDs(carprofen or meloxicam) reduces the minimum alveolar concentration(MAC) of sevoflurane during noxious stimulation in dogs(Yamashita et al.2008).The purpose of this study was to evaluate the effect of robenacoxib on the MAC for blunting adrenergic response(MAC-BAR) of sevoflurane in dogs.