【摘 要】
：
In this paper,A new type of DNA-based supramolecular hydrogel was prepared by simply mixing two components: polypeptide-DNA and G-quadruplex.We have success
【机 构】
：
Department of Chemistry,Tsinghua University,Beijing 100084
【出 处】
：
中国化学会第三届全国生物物理化学会议暨国际华人生物物理化学发展论坛
论文部分内容阅读
In this paper,A new type of DNA-based supramolecular hydrogel was prepared by simply mixing two components: polypeptide-DNA and G-quadruplex.We have successfully synthesized single-stranded DNA (ssDNA) grafted polypeptide via the copper-catalyzed click reaction.By introducing the intermolecular G-quadruplex structure,which are rich in guanine and are capable of forming a four-stranded structure in the presence of potassium,the hydrogel can be formed in a fast,in-situ manner and also obtain thermal and ionic responsive gel-sol transition,respectively.Due to its good biocompatibility,we expect this supramolecular hydrogel would have great potential applications in 3D printing and tissue engineering field.
其他文献
目的:对妇科阴道炎患者的护理干预方式以及干预效果进行调查.方法:以我院妇科64例阴道炎患者为调查样本,将其随机分为对照组、观察组,两组人数相等.对照组给予常规护理,观察
In this paper,traditional milling and discharge plasma-assisted milling are employed to synthesize aluminum nitride(AlN) powder at nanometer scale by milling th
目的:研究针刺联合康复护理在中风偏瘫侧足内翻患者中的应用效果.方法:选取研究对象为80例中风偏瘫侧足内翻患者,患者就诊时间段为2017年12月到2019年12月期间,按照随机分组
Chemical cross-linking provides an effective avenue to reduce the conformational entropy of polypeptide chains and hence has become a popular method to indu
This study highlights the synthesis of asymmetric Schiff base Zn(Ⅱ) complex,Zn2(L1)(L2)(en),which can be efficiently engendered by Watson-Crick base-pairin
在恶性肿瘤中甲状腺癌为最常见的一种,其主要治疗方式是需要手术切除.但是,手术治疗后患者就会出现一些负面情绪而且也会出现并发症,这些问题都会影响到患者的恢复情况,而且
目的:分析风险意识(risk awareness,RA)在手术室(operating room,OR)护理管理中的效果.方法:选取我院2018年12月-2019年12月期间收治的OR患者90例,根据随机抽样法分成两组,观
目的:研究规范化护理与视觉训练结合对于弱视儿童治疗依从性及视功能的影响效果.方法:选择2018年5月到2019年5月接受治疗的75例弱视儿童作为研究范例,利用随机数字分组法分为