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5. Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein

Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：tiantianle_a

【摘 要】

：

Autosomal dominant polycystic kidney disease(ADPKD)is a monogenetic disease that still lacks effective therapy.Repulsive guidance molecule b(RGMb),a co-receptor for bone morphogenetic proteins(BMPs)an

【作 者】

：

Jiangfeng Liu Weiling Wang Ming Liu Min Li Limin Su Hong Zhou Yin Xia Herbert Y.Lin Baoxue Yang 

【机 构】

：

State Key Laboratory of Natural and Biomimetic Drugs,Department of Pharmacology,School of Basic Medi

【出 处】

：

2016年国际生理学学术大会

【发表日期】

：

2016年6期

【关键词】

：

PKD Smad1/5/8 renal cyst kidney disease 

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　　Autosomal dominant polycystic kidney disease(ADPKD)is a monogenetic disease that still lacks effective therapy.Repulsive guidance molecule b(RGMb),a co-receptor for bone morphogenetic proteins(BMPs)and a ligand for neogenin,is expressed in renal tubular epithelial cells.

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